RESOURCES AND SUPPORT
When you were first diagnosed with HR+ early breast cancer, you and your doctor decided on an appropriate initial treatment, which may have included surgery, with or without radiation, and/or chemotherapy. Now you and your doctor may be considering a hormonal treatment (also called hormonal therapy) such as ARIMIDEX to reduce the risk of breast cancer recurrence.
In postmenopausal women, estrogen is mainly produced in other tissues such as liver, fat, muscle, and breast cells and not the ovaries. Estrogen produced in these tissues bind to estrogen receptors on breast cells causing the proliferation and growth of cancer cells. Aromatase inhibitors such as ARIMIDEX work by reducing the production of estrogen in these tissues by blocking the aromatase enzyme.
In postmenopausal women, aromatase, an enzyme found in liver, fat, muscle, and breast cancer cells, changes androgens into the hormone estrogen. Some breast cancer tumors grow when estrogen is present.
ARIMIDEX is an aromatase inhibitor that works by blocking aromatase, lowering the amount of the potentially cancer-causing estrogen in the body.
ARIMIDEX is approved for adjuvant treatment (treatment following surgery with or without radiation) of postmenopausal women with hormone receptor-positive early breast cancer.
ARIMIDEX is approved for the initial treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer and for the treatment of postmenopausal women with advanced breast cancer that has progressed following treatment with tamoxifen. Patients with hormone receptor-negative disease and patients who did not previously respond to tamoxifen therapy rarely responded to ARIMIDEX.
For more information, see your doctor.
Please see full Prescribing Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
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The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about ARIMIDEX, talk to your doctor or pharmacist. Only you and your health care professional can decide if ARIMIDEX is right for you.